Description

4-Bromo-6,8-Difluoro-2-Phenylquinoline is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its unique halogenated quinoline scaffold, which serves as a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, especially in kinase inhibitor and antimicrobial research.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and pesticides due to its bioactive quinoline core.
• Material Science Research: Serves as a precursor for organic light-emitting diodes (OLEDs) and other electronic materials where fluorinated quinolines are valued.
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands for metal catalysis and coordination chemistry.
• Chemical Biology Probes: Utilized to create fluorescent tags or molecular probes for studying biological processes.
• Academic & R&D: A versatile building block for methodological studies and the synthesis of complex natural product analogs in research laboratories.

Basic Information

Product Name	4-Bromo-6,8-Difluoro-2-Phenylquinoline
CAS No.	1189107-69-4
Molecular Formula	C₁₅H₈BrF₂N
Molecular Weight	328.14 g/mol
Synonyms	4-Bromo-6,8-difluoro-2-phenylquinoline; 2-Phenyl-4-bromo-6,8-difluoroquinoline; 4-Bromo-6,8-difluoro-2-phenyl-quinoline; Quinoline, 4-bromo-6,8-difluoro-2-phenyl-; 1189107-69-4; 4-Br-6,8-F2-2-Ph-quinoline
EINECS	Contact for details

Quality Control

Every batch of 4-Bromo-6,8-Difluoro-2-Phenylquinoline is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for research and scale-up applications. A detailed Certificate of Analysis (COA) including purity (HPLC), identity confirmation (NMR, IR), and impurity profile is available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.