Description

4-Bromo-5-Chloro-8-Methoxy-2-Methylquinoline is a high-purity, multi-substituted quinoline derivative that serves as a critical advanced intermediate in modern synthetic chemistry. Its complex halogenated and methoxylated structure makes it an invaluable building block for constructing sophisticated molecules with targeted biological and material properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors, antimicrobials, and other therapeutic agents.
• Agrochemical Research: Used in the development of new pesticides, herbicides, and fungicides, leveraging its halogenated quinoline core for bioactivity.
• Material Science: Serves as a building block for organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, due to its conjugated quinoline system.
• Chemical Synthesis: A versatile reagent for further functionalization, including cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to create complex molecular architectures.
• Academic & Industrial R&D: Essential for method development and discovery chemistry in university laboratories and corporate R&D centers globally.

Basic Information

Product Name	4-Bromo-5-Chloro-8-Methoxy-2-Methylquinoline
CAS No.	1189107-55-8
Molecular Formula	C₁₁H₉BrClNO
Molecular Weight	286.55 g/mol
Synonyms	4-Bromo-5-chloro-8-methoxy-2-methylquinoline; 2-Methyl-4-bromo-5-chloro-8-methoxyquinoline; 8-Methoxy-4-bromo-5-chloro-2-methylquinoline; Quinoline, 4-bromo-5-chloro-8-methoxy-2-methyl-; 1189107-55-8; 4-Bromo-5-chloro-8-methoxy-2-methyl-quinoline
EINECS	Contact for details

Quality Control

Our 4-Bromo-5-Chloro-8-Methoxy-2-Methylquinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry best practices for research-grade chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.