Description

4-Bromo-2-Methyl-8-Trifluoromethoxyquinoline is a high-value, multi-functional quinoline derivative, serving as a critical building block in advanced organic synthesis. Its unique halogenated and trifluoromethoxy-substituted structure makes it an indispensable intermediate for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Research: Used to develop new generations of herbicides, fungicides, and insecticides, leveraging the bioactivity of the quinoline core and the metabolic stability imparted by the fluorine atoms.
• Material Science: Serves as a monomer or functional additive in the creation of advanced organic electronic materials, such as OLEDs and conductive polymers.
• Ligand Synthesis: Useful for constructing complex nitrogen-containing ligands for catalysis and metal-organic frameworks (MOFs).
• Fluorescent Probe Development: The quinoline scaffold can be utilized to create sensitive fluorescent markers and sensors for biochemical assays.

Basic Information

Item	Details
Product Name	4-Bromo-2-Methyl-8-Trifluoromethoxyquinoline
CAS No.	1189107-44-5
Molecular Formula	C12H7BrF3NO
Molecular Weight	318.09 g/mol
Synonyms	4-Bromo-2-methyl-8-(trifluoromethoxy)quinoline; 8-Trifluoromethoxy-4-bromo-2-methylquinoline; 2-Methyl-4-bromo-8-trifluoromethoxyquinoline; Quinoline, 4-bromo-2-methyl-8-(trifluoromethoxy)-; 1189107-44-5
EINECS	Contact for details

Quality Control

Every batch of 4-Bromo-2-Methyl-8-Trifluoromethoxyquinoline is manufactured under strict quality management systems. We provide comprehensive analytical documentation, including a detailed Certificate of Analysis (COA) with results from HPLC, NMR, and GC-MS to verify identity, purity, and impurity profiles. Our quality assurance protocols are designed to meet the stringent requirements of research and pre-clinical development phases.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.