Description

4-Amino-8-Fluoro-2-Propylquinoline is a high-purity, advanced pharmaceutical intermediate characterized by its unique quinoline scaffold with strategically positioned amino and fluoro substituents. This compound is of significant commercial importance for its role in the synthesis of novel, biologically active molecules, particularly in medicinal chemistry. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, including kinase inhibitors and other small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of novel drug candidates, especially those targeting specific enzyme pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize the potency and selectivity of lead compounds.
• Kinase Inhibitor Development: Serves as a core scaffold for the design and production of potential kinase inhibitors due to the quinoline structure's affinity for ATP-binding sites.
• Agrochemical Research: Investigated as an intermediate for developing new active ingredients in crop protection products.
• Material Science: Potential precursor for the synthesis of specialized organic ligands or fluorescent markers used in analytical chemistry.

Basic Information

Product Name	4-Amino-8-Fluoro-2-Propylquinoline
CAS No.	1189107-32-1
Molecular Formula	C₁₂H₁₃FN₂
Molecular Weight	204.25 g/mol
Synonyms	8-Fluoro-4-amino-2-propylquinoline; 2-Propyl-8-fluoroquinolin-4-amine; 4-Amino-8-fluoro-2-propyl-quinoline; 8-Fluoro-2-propylquinolin-4-amine; Quinoline, 4-amino-8-fluoro-2-propyl-; 1189107-32-1; 4-Amino-8-fluoro-2-propylquinoline
EINECS	Contact for details

Quality Control

Our 4-Amino-8-Fluoro-2-Propylquinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our quality commitment supports applications in regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.