Description

6-Chloro-4-Hydroxy-8-Methoxyquinoline-3-Carboxylic Acid Ethyl Ester is a high-purity, advanced pharmaceutical intermediate with a distinct quinoline core structure. This compound is critical for research and development in medicinal chemistry, serving as a key building block for synthesizing novel active pharmaceutical ingredients (APIs). It is primarily sought by pharmaceutical manufacturers and R&D laboratories focused on developing new therapeutic agents, particularly in areas requiring complex heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Antimicrobial Agent Development: Serves as a core structure for synthesizing novel compounds with potential antibacterial or antifungal properties.
• Chemical Synthesis Reference Standard: Employed as a high-purity standard for analytical method development and quality control in chemical production.
• Organic Synthesis Building Block: Utilized in academic and industrial research for constructing more complex quinoline-based molecules.

Basic Information

Product Name	6-Chloro-4-Hydroxy-8-Methoxyquinoline-3-Carboxylic Acid Ethyl Ester
CAS No.	1189107-28-5
Molecular Formula	C₁₃H₁₂ClNO₄
Molecular Weight	281.69 g/mol
Synonyms	Ethyl 6-Chloro-4-hydroxy-8-methoxyquinoline-3-carboxylate; 6-Chloro-4-hydroxy-8-methoxy-3-quinolinecarboxylic Acid Ethyl Ester; 3-Quinolinecarboxylic acid, 6-chloro-4-hydroxy-8-methoxy-, ethyl ester; 8-Methoxy-6-chloro-4-hydroxyquinoline-3-carboxylic acid ethyl ester; 6-Chloro-8-methoxy-4-hydroxyquinoline-3-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our 6-Chloro-4-Hydroxy-8-Methoxyquinoline-3-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, confirming compliance with client specifications and industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.