Description

4-Amino-5-Chloro-8-Methoxyquinoline is a high-purity, multi-functional quinoline derivative of significant interest in advanced organic synthesis. This compound serves as a critical pharmaceutical intermediate and a versatile building block for the development of novel chemical entities. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting neurological and gastrointestinal pathways.
• Agrochemical Research: Used as a core scaffold for developing new generation fungicides and herbicides with enhanced efficacy.
• Chemical Synthesis Building Block: Essential for constructing complex heterocyclic compounds in medicinal chemistry and material science research.
• Ligand and Catalyst Development: Serves as a starting material for creating novel chelating ligands and organocatalysts.
• Dye and Pigment Intermediate: Utilized in the synthesis of specialized quinoline-based dyes and functional colorants.
• Academic and R&D: Employed in university and corporate laboratories for exploratory research in organic and bioorganic chemistry.

Basic Information

Product Name	4-Amino-5-Chloro-8-Methoxyquinoline
CAS No.	1189107-27-4
Molecular Formula	C10H9ClN2O
Molecular Weight	208.65 g/mol
Synonyms	8-Methoxy-5-chloroquinolin-4-amine; 5-Chloro-8-methoxy-4-quinolinamine; 4-Quinolinamine, 5-chloro-8-methoxy-; 4-Amino-5-chloro-8-methoxyquinoline; 5-Chloro-8-methoxyquinolin-4-amine
EINECS	Contact for details

Quality Control

Our 4-Amino-5-Chloro-8-Methoxyquinoline is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.