Description

4-Bromo-6-Chloro-8-Methyl-2-Phenylquinoline is a high-purity, multi-substituted quinoline derivative that serves as a critical advanced intermediate in modern organic synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in the development of novel pharmaceuticals and functional materials. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to introduce specific halogenated and aromatic functionalities into target molecules.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of potential drug candidates, especially in medicinal chemistry programs targeting kinase inhibitors, anti-cancer agents, and other biologically active heterocycles.
• Agrochemical Research: Used in the development of new active ingredients for crop protection products, leveraging its halogenated quinoline core.
• Material Science Precursor: Serves as a monomer or functional unit in the synthesis of organic semiconductors, light-emitting materials (OLEDs), and advanced polymers.
• Ligand Synthesis: The quinoline nitrogen and phenyl group make it a useful precursor for creating novel chelating ligands in coordination chemistry and catalysis.
• Chemical Biology Probe Development: Employed in the design and synthesis of molecular probes and fluorescent tags for biological imaging and diagnostic applications.
• Academic & Contract Research: A valuable reagent for methodological studies in cross-coupling reactions, C-H functionalization, and other cutting-edge synthetic transformations.

Basic Information

Product Name	4-Bromo-6-Chloro-8-Methyl-2-Phenylquinoline
CAS No.	1189107-23-0
Molecular Formula	C₁₆H₁₁BrClN
Molecular Weight	332.62 g/mol
Synonyms	4-Bromo-6-chloro-8-methyl-2-phenylquinoline; 2-Phenyl-4-bromo-6-chloro-8-methylquinoline; Quinoline, 4-bromo-6-chloro-8-methyl-2-phenyl-; 1189107-23-0; 4-Br-6-Cl-8-Me-2-Ph-quinoline
EINECS	Contact for details

Quality Control

Our 4-Bromo-6-Chloro-8-Methyl-2-Phenylquinoline is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support our clients' regulatory needs and can supply material suitable for research and development under cGMP guidelines as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.