Description

4-Amino-5,7-Difluoro-2-Phenylquinoline is a high-purity, functionalized quinoline derivative of significant interest in advanced organic synthesis. This compound serves as a critical pharmaceutical intermediate and a versatile building block for the development of novel active compounds. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science sectors seeking to incorporate its unique difluoro-substituted quinoline scaffold into new molecular entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and anti-infective therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, leveraging its heterocyclic structure for bioactivity.
• Material Science & OLED Development: Acts as an electron-transporting or emitting layer component in the research of organic light-emitting diodes (OLEDs) and other electronic materials.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Fluorescent Probe & Dye Chemistry: Serves as a core structure for developing novel fluorescent markers and dyes used in biochemical sensing and imaging.
• Academic & Contract Research: A valuable reagent for synthetic organic chemistry research in universities and contract research organizations (CROs).

Basic Information

Product Name	4-Amino-5,7-Difluoro-2-Phenylquinoline
CAS No.	1189107-01-4
Molecular Formula	C15H10F2N2
Molecular Weight	256.25 g/mol
Synonyms	4-Amino-5,7-difluoro-2-phenylquinoline; 2-Phenyl-5,7-difluoroquinolin-4-amine; 5,7-Difluoro-4-amino-2-phenylquinoline; 4-Amino-2-phenyl-5,7-difluoroquinoline; Quinoline, 4-amino-5,7-difluoro-2-phenyl-; 1189107-01-4; 4-Amino-5,7-difluoro-2-phenyl-quinoline
EINECS	Contact for details

Quality Control

Our 4-Amino-5,7-Difluoro-2-Phenylquinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee batch-to-batch consistency and traceability, meeting the stringent requirements of research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation from moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.