Description

4-Bromo-2-Phenyl-7-Trifluoromethoxyquinoline is a high-value, multi-functional heterocyclic building block and advanced pharmaceutical intermediate. Its unique molecular structure, featuring bromine, phenyl, and trifluoromethoxy substituents on a quinoline core, makes it a critical precursor for synthesizing complex molecules with tailored biological activity. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly in oncology, antiviral, and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Serves as a building block for creating new pesticides, herbicides, and fungicides with enhanced efficacy and selectivity.
• Material Science: Used in the synthesis of organic light-emitting diodes (OLEDs) and other advanced electronic materials due to its electron-transporting quinoline scaffold.
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to construct more complex molecular architectures for various R&D purposes.
• Ligand and Catalyst Development: Acts as a precursor for nitrogen-containing ligands used in homogeneous catalysis.
• Life Science Research: Utilized as a fluorescent probe or tag in biochemical assays and diagnostic research.

Basic Information

Product Name	4-Bromo-2-Phenyl-7-Trifluoromethoxyquinoline
CAS No.	1189106-98-6
Molecular Formula	C₁₇H₁₀BrF₃NO
Molecular Weight	381.17 g/mol
Synonyms	4-Bromo-2-phenyl-7-(trifluoromethoxy)quinoline; 7-(Trifluoromethoxy)-4-bromo-2-phenylquinoline; 2-Phenyl-4-bromo-7-trifluoromethoxyquinoline; Quinoline, 4-bromo-2-phenyl-7-(trifluoromethoxy)-; 1189106-98-6; 4-Br-2-Ph-7-OCF3-Quinoline
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Phenyl-7-Trifluoromethoxyquinoline is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP standards for pharmaceutical applications and can provide regulatory support documentation upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.