Description

4-Bromo-2-Phenyl-6-Trifluoromethoxyquinoline is a specialized quinoline derivative, a high-value intermediate in advanced organic synthesis. Its unique halogenated and trifluoromethoxy-substituted structure makes it a critical building block for the development of novel active compounds. This product is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries seeking to create new molecules with enhanced biological activity and physicochemical properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors, antiviral agents, and other therapeutic small molecules.
• Agrochemical Research: Used in the development of new pesticides, herbicides, and fungicides, where the quinoline scaffold and halogen atoms can contribute to bioactivity and environmental stability.
• Material Science: Serves as a building block for organic electronic materials, such as ligands for OLEDs (Organic Light-Emitting Diodes) or components for advanced polymers, leveraging its conjugated system.
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) due to the reactive bromine atom, enabling the construction of complex molecular architectures.
• Fluorescent Probe Development: The quinoline core can be utilized to develop fluorescent dyes or sensors for biochemical and diagnostic applications.

Basic Information

Product Name	4-Bromo-2-Phenyl-6-Trifluoromethoxyquinoline
CAS No.	1189106-96-4
Molecular Formula	C₁₇H₉BrF₃NO
Molecular Weight	380.16 g/mol
Synonyms	4-Bromo-2-phenyl-6-(trifluoromethoxy)quinoline; 6-(Trifluoromethoxy)-4-bromo-2-phenylquinoline; 2-Phenyl-4-bromo-6-trifluoromethoxyquinoline; Quinoline, 4-bromo-2-phenyl-6-(trifluoromethoxy)-; 1189106-96-4; 4-Br-2-Ph-6-OCF3-Quinoline
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Phenyl-6-Trifluoromethoxyquinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with detailed results from techniques such as HPLC, NMR, and GC-MS. Our commitment is to supply material that meets the exacting standards required for research and development as well as scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥97.0%
Related Substances (HPLC)	Total impurities ≤3.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.