Description

7-Bromo-2,8-Dimethylquinoline-3-Carboxylic Acid Ethyl Ester is a high-purity, functionalized quinoline derivative serving as a critical advanced intermediate in organic synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) and functional materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific bromo and ester functionalities into quinoline-based scaffolds.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of potential drug candidates, especially in medicinal chemistry programs targeting kinase inhibitors, antimicrobial agents, and other therapeutic small molecules.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, where the quinoline core can contribute to biological activity.
• Material Science Precursor: Serves as a starting material for creating organic ligands, dyes, or photoactive compounds used in advanced materials.
• Chemical Synthesis Reagent: Employed in cross-coupling reactions (e.g., Suzuki, Heck) where the bromo substituent acts as a reactive handle for further functionalization.
• Academic & Industrial R&D: Essential for method development and exploring new synthetic pathways in university and corporate research laboratories.

Basic Information

Product Name	7-Bromo-2,8-Dimethylquinoline-3-Carboxylic Acid Ethyl Ester
CAS No.	1189106-91-9
Molecular Formula	C₁₄H₁₄BrNO₂
Molecular Weight	308.17 g/mol
Synonyms	Ethyl 7-Bromo-2,8-dimethylquinoline-3-carboxylate; 7-Bromo-2,8-dimethylquinoline-3-carboxylic acid ethyl ester; 3-Quinolinecarboxylic acid, 7-bromo-2,8-dimethyl-, ethyl ester; 7-Bromo-2,8-dimethyl-3-quinolinecarboxylic acid ethyl ester; Ethyl 7-bromo-2,8-dimethyl-3-quinolinecarboxylate; 1189106-91-9; 7-Bromo-2,8-dimethylquinoline ethyl-3-carboxylate
EINECS	Contact for details

Quality Control

Our 7-Bromo-2,8-Dimethylquinoline-3-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.