Description

4-Amino-7,8-Difluoro-2-Propylquinoline is a high-purity, functionalized quinoline derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs), particularly for fluoroquinolone antibiotics and other therapeutic agents. Pharmaceutical R&D laboratories, agrochemical manufacturers, and specialty chemical producers need this material for its precise molecular architecture, which enables the construction of complex molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel fluoroquinolone antibiotic candidates and other drug molecules.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging the biological activity of the quinoline core.
• Material Science: Serves as a monomer or functional additive in the creation of specialty polymers and advanced organic materials.
• Chemical Synthesis: Employed as a versatile building block for constructing more complex heterocyclic compounds in academic and industrial research.
• Dye & Pigment Industry: Acts as an intermediate for synthesizing specialized fluorinated quinoline-based dyes and colorants.

Basic Information

Product Name	4-Amino-7,8-Difluoro-2-Propylquinoline
CAS No.	1189106-87-3
Molecular Formula	C₁₂H₁₂F₂N₂
Molecular Weight	222.24 g/mol
Synonyms	2-Propyl-4-amino-7,8-difluoroquinoline; 7,8-Difluoro-4-amino-2-propylquinoline; 4-Amino-7,8-difluoro-2-propyl-1H-quinoline; 4-Amino-7,8-difluoro-2-propylquinoline; 1189106-87-3; 4-Amino-7,8-difluoro-2-propyl-quinoline; 2-Propyl-7,8-difluoroquinolin-4-amine
EINECS	Contact for details

Quality Control

Our 4-Amino-7,8-Difluoro-2-Propylquinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical intermediate applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.