Description

4-Bromo-2-Propyl-7-Trifluoromethoxyquinoline is a high-value, multi-functional quinoline derivative designed for advanced chemical synthesis. This compound serves as a critical pharmaceutical intermediate and organic building block, enabling the development of novel active ingredients and functional materials. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific bromo, alkyl, and trifluoromethoxy functionalities into complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the biological activity of the quinoline core and halogen substituents.
• Material Science: Serves as a building block for advanced organic materials, such as organic light-emitting diodes (OLEDs) and liquid crystals, where the trifluoromethoxy group can influence electronic properties.
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) due to the reactive bromine atom, allowing for further functionalization.
• Academic & Contract Research: A valuable reagent for medicinal chemistry programs and structure-activity relationship (SAR) studies in university and CRO laboratories.

Basic Information

Product Name	4-Bromo-2-Propyl-7-Trifluoromethoxyquinoline
CAS No.	1189106-77-1
Molecular Formula	C₁₄H₁₃BrF₃NO
Molecular Weight	348.16 g/mol
Synonyms	4-Bromo-2-propyl-7-(trifluoromethoxy)quinoline; 7-(Trifluoromethoxy)-4-bromo-2-propylquinoline; 2-Propyl-4-bromo-7-trifluoromethoxyquinoline; 4-Bromo-2-propyl-7-trifluoromethoxyquinoline; 1189106-77-1; Quinoline, 4-bromo-2-propyl-7-(trifluoromethoxy)-
EINECS	Contact for details

Quality Control

Every batch of 4-Bromo-2-Propyl-7-Trifluoromethoxyquinoline is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and consistency for your critical research and development processes. Certificates of Analysis (COA) detailing purity by HPLC, identity confirmation (NMR, IR), and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.