Description

4-Bromo-7,8-Difluoro-2-Phenylquinoline is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its unique halogenated and fluorinated quinoline structure, which serves as a critical precursor for constructing complex molecular architectures with tailored electronic and steric properties. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries, particularly for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, especially in kinase inhibitor and antiviral research programs.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and pesticides, leveraging the bioactivity of the quinoline core.
• Organic Light-Emitting Diode (OLED) Materials: Serves as a building block for electron-transporting or host materials in display and lighting technologies.
• Ligand and Catalyst Development: Utilized in organometallic chemistry to create novel ligands for catalysis and sensing applications.
• Fluorescent Probe and Dye Synthesis: The fluorinated quinoline scaffold is ideal for developing sensitive chemical probes and specialty dyes.
• Academic and R&D: A valuable reagent for methodological studies in cross-coupling reactions and fluorination chemistry.

Basic Information

Product Name	4-Bromo-7,8-Difluoro-2-Phenylquinoline
CAS No.	1189106-68-0
Molecular Formula	C15H8BrF2N
Molecular Weight	320.13 g/mol
Synonyms	4-Bromo-7,8-difluoro-2-phenylquinoline; 2-Phenyl-4-bromo-7,8-difluoroquinoline; 1189106-68-0; 4-Bromo-7,8-difluoro-2-phenyl-quinoline; Quinoline, 4-bromo-7,8-difluoro-2-phenyl-; 4-Br-7,8-F2-2-Ph-quinoline
EINECS	Contact for details

Quality Control

Our 4-Bromo-7,8-Difluoro-2-Phenylquinoline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality parameters. Our commitment to supply reliability and traceability supports your R&D and scale-up processes with confidence.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.