Description

4-Bromo-7,8-Difluoroquinoline is a high-purity, multi-functional halogenated quinoline derivative, serving as a critical building block in advanced organic synthesis. Its unique molecular structure, featuring bromine and fluorine substituents, makes it an indispensable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly in the development of kinase inhibitors, antibacterial agents, and other small-molecule therapeutics.
• Agrochemical Research: Used to construct novel fungicides, herbicides, and pesticides, leveraging the bioactivity of the quinoline core and halogen atoms.
• Material Science: Serves as a building block for organic semiconductors, liquid crystals, and fluorescent dyes due to its electron-deficient aromatic system.
• Chemical Synthesis: Acts as a versatile intermediate for cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic substitutions to introduce further complexity.
• Ligand Synthesis: Utilized in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	4-Bromo-7,8-Difluoroquinoline
CAS No.	1189106-43-1
Molecular Formula	C9H4BrF2N
Molecular Weight	244.04 g/mol
Synonyms	7,8-Difluoro-4-bromoquinoline; 4-Bromo-7,8-difluoroquinoline; Quinoline, 4-bromo-7,8-difluoro-; 1189106-43-1
EINECS	Contact for details

Quality Control

Our 4-Bromo-7,8-Difluoroquinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry standards for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.