Description

4-Amino-6,8-Difluoro-2-Phenylquinoline is a high-value, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its unique molecular architecture, which combines a quinoline scaffold with strategic fluorine and amino substituents, enabling precise modulation of electronic and steric properties. This compound is critically needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly for kinase inhibitors, antimicrobials, and anticancer agents.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and pesticides, where the fluorine atoms enhance bioavailability and metabolic stability.
• Material Science: Acts as a building block for organic semiconductors, light-emitting diodes (OLEDs), and other electronic materials due to its conjugated quinoline system.
• Chemical Biology: Employed as a fluorescent probe or tag due to the inherent photophysical properties of the quinoline core.
• Academic & Contract Research: Essential for methodological studies in organic chemistry, including novel cross-coupling and cyclization reactions.

Basic Information

Product Name	4-Amino-6,8-Difluoro-2-Phenylquinoline
CAS No.	1189106-40-8
Molecular Formula	C15H10F2N2
Molecular Weight	256.25 g/mol
Synonyms	2-Phenyl-4-amino-6,8-difluoroquinoline; 6,8-Difluoro-4-amino-2-phenylquinoline; 4-Amino-6,8-difluoro-2-phenylquinoline; 1189106-40-8; Quinoline, 4-amino-6,8-difluoro-2-phenyl-; 2-Phenyl-6,8-difluoroquinolin-4-amine
EINECS	Contact for details

Quality Control

Every batch of 4-Amino-6,8-Difluoro-2-Phenylquinoline is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and development. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for all shipments. Our quality commitment supports compliance with cGMP and ISO 9001 standards where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). This compound may be light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.