Description

4-Amino-6-Fluoro-2-Propylquinoline is a high-purity, fluorinated quinoline derivative serving as a critical building block in advanced organic synthesis. Its value lies in the strategic combination of an amino group and a fluorine atom on the quinoline scaffold, enabling precise molecular modifications for developing novel compounds. This intermediate is essential for research and development in the pharmaceutical and agrochemical industries, particularly for creating active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, especially in kinase inhibitor and antimicrobial programs.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and pesticides, leveraging the bioactivity of the quinoline core.
• Material Science Research: Serves as a precursor for developing organic semiconductors, fluorescent dyes, and photoactive materials.
• Chemical Research & Development: A versatile building block for medicinal chemistry, enabling structure-activity relationship (SAR) studies and library synthesis.
• Ligand and Catalyst Development: Utilized in the synthesis of complex ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	4-Amino-6-Fluoro-2-Propylquinoline
CAS No.	1189106-32-8
Molecular Formula	C₁₂H₁₃FN₂
Molecular Weight	204.25 g/mol
Synonyms	2-Propyl-6-fluoro-4-quinolinamine; 6-Fluoro-2-propyl-4-quinolinamine; 4-Quinolinamine, 6-fluoro-2-propyl-; 4-Amino-6-fluoro-2-propylquinoline; 6-Fluoro-2-propylquinolin-4-amine; 1189106-32-8; 4-Amino-6-fluoro-2-propyl-quinoline
EINECS	Contact for details

Quality Control

Our 4-Amino-6-Fluoro-2-Propylquinoline is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.