Description

4-Bromo-5-Chloro-8-Methyl-2-Phenylquinoline is a high-purity, multi-substituted quinoline derivative that serves as a critical advanced intermediate in modern synthetic chemistry. Its complex halogenated and phenyl-substituted structure makes it a valuable building block for constructing sophisticated molecular architectures. This compound is primarily sought after by research institutions and pharmaceutical R&D departments for the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting neurological disorders and oncology.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and pesticides due to its bioactive quinoline core.
• Material Science: Serves as a building block for organic light-emitting diodes (OLEDs) and other electronic materials where specific photophysical properties are required.
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and as a ligand precursor in catalysis research.
• Academic & Industrial R&D: Essential for methodological studies in organic chemistry and for creating compound libraries for high-throughput screening.

Basic Information

Product Name	4-Bromo-5-Chloro-8-Methyl-2-Phenylquinoline
CAS No.	1189106-24-8
Molecular Formula	C₁₆H₁₁BrClN
Molecular Weight	340.62 g/mol
Synonyms	4-Bromo-5-chloro-8-methyl-2-phenylquinoline; 2-Phenyl-4-bromo-5-chloro-8-methylquinoline; Quinoline, 4-bromo-5-chloro-8-methyl-2-phenyl-; 1189106-24-8; 4-Br-5-Cl-8-Me-2-Ph-quinoline
EINECS	Contact for details

Quality Control

Our 4-Bromo-5-Chloro-8-Methyl-2-Phenylquinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications. Our quality commitment supports applications requiring high-purity intermediates for regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.