Description

4-Amino-2-Phenyl-6-Trifluoromethylquinoline is a high-purity, specialized quinoline derivative distinguished by its trifluoromethyl and amino functional groups. This compound is valued for its role as a critical synthetic intermediate in advanced organic chemistry and pharmaceutical research. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Research: Used in developing advanced active ingredients for crop protection, leveraging the stability imparted by the trifluoromethyl group.
• Material Science Precursor: Serves as a monomer or functional unit in the development of organic electronic materials, such as OLEDs and conductive polymers.
• Ligand Synthesis: Utilized for creating complex nitrogen-containing ligands for catalysis and coordination chemistry.
• Fluorescent Probe Development: The quinoline core makes it suitable for research into new fluorescent dyes and sensors.
• Academic & Contract Research: Essential for fundamental organic synthesis studies and custom synthesis projects in CROs (Contract Research Organizations).

Basic Information

Product Name	4-Amino-2-Phenyl-6-Trifluoromethylquinoline
CAS No.	1189106-21-5
Molecular Formula	C₁₆H₁₁F₃N₂
Molecular Weight	288.27 g/mol
Synonyms	4-Amino-2-phenyl-6-(trifluoromethyl)quinoline; 6-(Trifluoromethyl)-2-phenylquinolin-4-amine; 2-Phenyl-6-trifluoromethylquinolin-4-ylamine; 4-Amino-2-phenyl-6-trifluoromethyl-quinoline; 4-Amino-2-phenyl-6-(trifluoromethyl)quinoline; 1189106-21-5; 4-Amino-2-phenyl-6-trifluoromethyl quinoline
EINECS	Contact for details

Quality Control

Our 4-Amino-2-Phenyl-6-Trifluoromethylquinoline is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and relevant research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.