Description

4-Amino-7-Fluoro-2-Phenylquinoline is a high-purity, functionalized quinoline derivative that serves as a critical advanced intermediate in organic synthesis. Its unique molecular architecture, featuring both amino and fluoro substituents on the quinoline core, makes it a versatile building block for constructing complex molecules with tailored properties. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting neurological disorders, cancers, and infectious diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the quinoline scaffold.
• Material Science: Serves as a building block for creating organic semiconductors, light-emitting diodes (OLEDs), and other functional organic electronic materials.
• Ligand Synthesis: The amino group allows for functionalization to create novel ligands for catalysis and metal-organic frameworks (MOFs).
• Fluorescent Probe Development: The fluorinated quinoline structure is valuable for designing fluorescent dyes and molecular probes for bioimaging and sensing applications.
• Academic & Contract Research: Essential for methodological studies in organic chemistry and for contract research organizations (CROs) supporting drug discovery pipelines.

Basic Information

Product Name	4-Amino-7-Fluoro-2-Phenylquinoline
CAS No.	1189106-13-5
Molecular Formula	C15H11FN2
Molecular Weight	238.26 g/mol
Synonyms	7-Fluoro-2-phenylquinolin-4-amine; 2-Phenyl-7-fluoroquinolin-4-amine; 4-Amino-7-fluoro-2-phenylquinoline; 4-Amino-2-phenyl-7-fluoroquinoline; 7-Fluoro-4-amino-2-phenylquinoline; 2-Phenyl-4-amino-7-fluoroquinoline; 4-Quinolinamine, 7-fluoro-2-phenyl-; 1189106-13-5
EINECS	Contact for details

Quality Control

Every batch of 4-Amino-7-Fluoro-2-Phenylquinoline is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We ensure compliance with stringent internal specifications that are aligned with ICH guidelines for impurities. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and impurity profiles as determined by HPLC, NMR, and MS.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.