Description

4-Bromo-2-Phenyl-7-Trifluoromethylquinoline is a high-value, multi-functional heterocyclic building block characterized by its bromine and trifluoromethyl substituents. This compound matters for its role as a critical intermediate in the synthesis of advanced materials and active pharmaceutical ingredients (APIs), where its unique halogenated and fluorinated structure enables precise molecular modifications. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing novel compounds with targeted properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other therapeutic agents.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the quinoline scaffold and halogen atoms contribute to biological activity.
• Material Science: Serves as a building block for organic electronic materials, such as OLED (Organic Light-Emitting Diode) emitters or charge-transport materials, due to its rigid, conjugated structure.
• Chemical Synthesis: Utilized in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) where the bromine atom acts as a handle for further functionalization.
• Fluorine Chemistry Studies: Employed as a model compound in research exploring the effects of the trifluoromethyl group on reactivity, stability, and physicochemical properties.

Basic Information

Product Name	4-Bromo-2-Phenyl-7-Trifluoromethylquinoline
CAS No.	1189106-12-4
Molecular Formula	C₁₆H₉BrF₃N
Molecular Weight	352.15 g/mol
Synonyms	4-Bromo-2-phenyl-7-(trifluoromethyl)quinoline; 7-Trifluoromethyl-4-bromo-2-phenylquinoline; 2-Phenyl-4-bromo-7-trifluoromethylquinoline; 4-Bromo-2-phenyl-7-trifluoromethyl-quinoline; Quinoline, 4-bromo-2-phenyl-7-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Phenyl-7-Trifluoromethylquinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from incompatible materials. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.