Description

4-Bromo-2-Phenyl-6-Trifluoromethylquinoline is a high-value, multi-functional heterocyclic building block characterized by its bromine, phenyl, and trifluoromethyl substituents. This compound matters for its role as a critical intermediate in the synthesis of advanced materials and active pharmaceutical ingredients (APIs), where its unique structure enables precise molecular modifications. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing novel compounds with targeted properties.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, leveraging the biological activity of the quinoline core.
• Material Science: Acts as a building block for organic light-emitting diodes (OLEDs) and other electronic materials due to its electron-deficient quinoline structure.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology: Utilized as a fluorescent probe or tag in biochemical assays and diagnostic research.
• Academic & R&D: A valuable reagent for methodological studies in organic synthesis, including cross-coupling and functional group transformations.

Basic Information

Product Name	4-Bromo-2-Phenyl-6-Trifluoromethylquinoline
CAS No.	1189106-10-2
Molecular Formula	C₁₆H₉BrF₃N
Molecular Weight	352.15 g/mol
Synonyms	4-Bromo-2-phenyl-6-(trifluoromethyl)quinoline; 6-Trifluoromethyl-4-bromo-2-phenylquinoline; 2-Phenyl-4-bromo-6-trifluoromethylquinoline; Quinoline, 4-bromo-2-phenyl-6-(trifluoromethyl)-; 1189106-10-2; 4-Br-2-Ph-6-CF3-Quinoline
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Phenyl-6-Trifluoromethylquinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with all shipments, detailing batch-specific results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.