Description

4-[4-(Trifluoromethyl)Phenoxy]Benzylamine Hcl CAS NO 1188479-28-8 is a high-purity, trifluoromethyl-substituted aromatic amine hydrochloride salt, serving as a critical advanced pharmaceutical intermediate and versatile building block in organic synthesis. Its core value lies in the unique properties imparted by the trifluoromethylphenoxy moiety, which is highly sought after for enhancing the metabolic stability, lipophilicity, and bioavailability of target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in therapeutic areas targeting the central nervous system, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where the trifluoromethyl group can improve activity and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing specialized aromatic amines used in electronic display technologies and organic light-emitting diodes.
• Polymer & Resin Modifier: Incorporated into polymer chains to alter thermal, chemical, or surface properties for high-performance coatings and engineering plastics.
• Chemical Research & Development: A versatile reagent for constructing complex molecular architectures in academic and industrial R&D laboratories.
• Fluorinated Compound Library Synthesis: Critical for creating focused libraries of fluorinated compounds for high-throughput screening in drug discovery.

Basic Information

Product Name	4-[4-(Trifluoromethyl)Phenoxy]Benzylamine Hydrochloride
CAS No.	1188479-28-8
Molecular Formula	C14H12F3NO•HCl
Molecular Weight	303.71 g/mol (Free base: 267.25 g/mol)
Synonyms	1-[[4-[4-(Trifluoromethyl)phenoxy]phenyl]methyl]amine hydrochloride; 4-((4-(Trifluoromethyl)phenoxy)benzylamine hydrochloride; [4-[4-(Trifluoromethyl)phenoxy]phenyl]methanamine hydrochloride; Benzylamine, 4-[4-(trifluoromethyl)phenoxy]-, hydrochloride; 4-(4-Trifluoromethylphenoxy)benzylamine HCl; α-Amino-4'-(α,α,α-trifluoro-p-tolyloxy)toluene hydrochloride
EINECS	Contact for details

Quality Control

Our 4-[4-(Trifluoromethyl)Phenoxy]Benzylamine HCl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP principles where applicable to support our clients in regulated industry segments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.