Description

6-Bromoquinoline-5-Carbonitrile is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. Its unique bromo-cyano substituted quinoline scaffold makes it a critical intermediate for constructing complex molecular architectures. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for applications ranging from drug discovery to the development of functional organic materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Material Science: Acts as a building block for organic semiconductors, liquid crystals, and photoactive materials due to its electron-deficient quinoline structure.
• Chemical Biology: Employed in the creation of molecular probes and fluorescent tags for studying biological processes.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for Suzuki, Stille, and Buchwald-Hartwig amination reactions to introduce complex functionalities.
• Ligand Synthesis: Useful for preparing novel chelating ligands in coordination chemistry and catalysis.

Basic Information

Product Name	6-Bromoquinoline-5-Carbonitrile
CAS No.	1188365-70-9
Molecular Formula	C10H5BrN2
Molecular Weight	233.07 g/mol
Synonyms	6-Bromo-5-cyanoquinoline; 5-Cyano-6-bromoquinoline; Quinoline, 6-bromo-5-cyano-; 6-Bromoquinoline-5-carbonitrile; 1188365-70-9; 6-Bromo-5-quinolinecarbonitrile
EINECS	Contact for details

Quality Control

Our 6-Bromoquinoline-5-Carbonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.