Description

1-(Benzyloxy)-3-Bromo-5-Chlorobenzene is a high-purity halogenated aromatic ether building block of significant importance in advanced organic synthesis. This compound matters as a versatile intermediate, enabling the precise introduction of benzyl-protected phenolic and halogenated functionalities into complex molecular architectures. Pharmaceutical, agrochemical, and material science researchers need it for developing active ingredients, ligands, and specialty polymers.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized phosphine or nitrogen-based ligands used in transition metal catalysis.
• Material Science: Employed in the synthesis of monomers for high-performance polymers, liquid crystals, and organic electronic materials.
• Chemical Research: A valuable reagent for Suzuki, Buchwald-Hartwig, and other cross-coupling reactions to construct biaryl systems.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and development of scalable synthetic routes.

Basic Information

Product Name	1-(Benzyloxy)-3-Bromo-5-Chlorobenzene
CAS No.	1187966-48-8
Molecular Formula	C₁₃H₁₀BrClO
Molecular Weight	297.57 g/mol
Synonyms	3-Bromo-5-chlorophenyl benzyl ether; Benzyl 3-bromo-5-chlorophenyl ether; 1-Bromo-3-(benzyloxy)-5-chlorobenzene; 3-Bromo-5-chloro-1-(phenylmethoxy)benzene; 1-(Benzyloxy)-3-bromo-5-chloro-benzene; (3-Bromo-5-chlorophenoxy)methyl]benzene
EINECS	Contact for details

Quality Control

Our 1-(Benzyloxy)-3-Bromo-5-Chlorobenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications in GMP and ISO-compliant environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.