Description

4,4-Dimethyl-1,2,3,4-tetrahydro-quinolin-6-ylamine is a high-purity, synthetically valuable organic intermediate featuring a functionalized tetrahydroquinoline scaffold. This compound matters for its role as a critical building block in the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors seeking to incorporate this specific amine-substituted heterocyclic structure into their target compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders or possessing kinase inhibitory activity.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that utilize the tetrahydroquinoline core for biological activity.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of advanced organic polymers, dyes, and photoactive materials.
• Ligand and Catalyst Development: Employed in the creation of novel chiral ligands or organocatalysts for asymmetric synthesis applications.
• Chemical Biology Probes: Utilized as a scaffold for developing molecular probes to study biological pathways and protein functions.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) conducting exploratory chemistry and method development.

Basic Information

Product Name	4,4-Dimethyl-1,2,3,4-tetrahydro-quinolin-6-ylamine
CAS No.	1187933-52-3
Molecular Formula	C11H16N2
Molecular Weight	176.26 g/mol
Synonyms	6-Amino-4,4-dimethyl-1,2,3,4-tetrahydroquinoline; 4,4-Dimethyl-1,2,3,4-tetrahydroquinolin-6-amine; 4,4-Dimethyl-1,2,3,4-tetrahydro-6-quinolinamine; 4,4-Dimethyl-5,6,7,8-tetrahydroquinazolin-2-amine (related structure); 6-Amino-4,4-dimethyl-1,2,3,4-tetrahydro-quinoline; 4,4-DMTQ-6-Amine; DTQ-6-NH2
EINECS	Contact for details

Quality Control

Our 4,4-Dimethyl-1,2,3,4-tetrahydro-quinolin-6-ylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support compliance with cGMP and ICH Q7 guidelines for advanced intermediates, ensuring reliability for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥97.0% (Area %)
Purity (HPLC)	≥98.0% (Total area)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.