Description

6-Formyl-3,4-Dihydro-2H-Quinoline-1-Carboxylic Acid tert-Butyl Ester is a versatile and high-value advanced pharmaceutical intermediate, primarily utilized in the synthesis of complex bioactive molecules. Its core value lies in its formyl and protected carboxylic acid functional groups, which serve as key handles for constructing intricate heterocyclic scaffolds. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly those focused on creating novel quinoline-based drug candidates and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of active pharmaceutical ingredients (APIs) targeting various therapeutic areas.
• Organic Synthesis Reagent: Used in multi-step synthesis for constructing complex heterocyclic compounds, leveraging its reactive aldehyde group for condensation and cyclization reactions.
• Agrochemical Research: Serves as a precursor in the development of new herbicides, fungicides, and insecticides with quinoline-based structures.
• Material Science: Potential use in the synthesis of organic ligands for catalysts or functional materials.
• Academic & R&D: A valuable compound for medicinal chemistry research and process development in university and industrial laboratories.

Basic Information

Product Name	6-Formyl-3,4-Dihydro-2H-Quinoline-1-Carboxylic Acid tert-Butyl Ester
CAS No.	1187933-34-1
Molecular Formula	C15H17NO3
Molecular Weight	259.30 g/mol
Synonyms	1-Boc-6-formyl-1,2,3,4-tetrahydroquinoline; tert-Butyl 6-formyl-3,4-dihydro-2H-quinoline-1-carboxylate; 6-Formyl-1,2,3,4-tetrahydroquinoline-1-carboxylic acid tert-butyl ester; 1,2,3,4-Tetrahydroquinoline-1-carboxylic acid, 6-formyl-, 1,1-dimethylethyl ester; 1-N-Boc-6-formyl-1,2,3,4-tetrahydroquinoline; Boc-6-formyl-THQ; 6-Formyl-THQ-Boc
EINECS	Contact for details

Quality Control

Our 6-Formyl-3,4-Dihydro-2H-Quinoline-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our production adheres to cGMP guidelines where applicable, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C for long-term stability. This compound is easily oxidized and light-sensitive; allow the container to reach ambient temperature before opening to minimize moisture condensation and exposure to air.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.