Description

4,4-Dimethyl-2-Oxo-1,2,3,4-Tetrahydro-Quinoline-6-Carboxylic Acid Methyl Ester is a high-purity, synthetically valuable tetrahydroquinoline derivative, serving as a critical advanced intermediate in modern organic synthesis. Its core value lies in providing a functionalized, fused-ring scaffold essential for constructing complex molecules with targeted biological activity. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and infectious diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the quinoline core.
• Material Science Precursor: Serves as a monomer or functional additive in the research of advanced polymers and organic electronic materials.
• Chemical Synthesis Scaffold: Utilized in medicinal and combinatorial chemistry for library synthesis and structure-activity relationship (SAR) studies.
• Dye & Pigment Intermediate: Acts as a precursor in the synthesis of specialized quinoline-based dyes and colorants.

Basic Information

Product Name	4,4-Dimethyl-2-Oxo-1,2,3,4-Tetrahydro-Quinoline-6-Carboxylic Acid Methyl Ester
CAS No.	1187933-23-8
Molecular Formula	C₁₃H₁₅NO₃
Molecular Weight	233.26 g/mol
Synonyms	Methyl 4,4-dimethyl-2-oxo-1,2,3,4-tetrahydroquinoline-6-carboxylate; 6-(Methoxycarbonyl)-4,4-dimethyl-1,2,3,4-tetrahydro-2-quinolone; 4,4-Dimethyl-1,2,3,4-tetrahydro-2-oxoquinoline-6-carboxylic Acid Methyl Ester; 4,4-Dimethyl-2-oxo-1,2,3,4-tetrahydroquinoline-6-methyl carboxylate; 1187933-23-8; 4,4-Dimethyl-2-oxo-1,2,3,4-tetrahydroquinoline-6-carboxylic acid, methyl ester
EINECS	Contact for details

Quality Control

Our 4,4-Dimethyl-2-Oxo-1,2,3,4-Tetrahydro-Quinoline-6-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment supports applications requiring GMP-grade intermediates and research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.