Description

7-Bromo-1-Methylquinolin-2(1H)-One is a high-purity brominated quinolinone derivative, a crucial advanced intermediate in modern organic synthesis. This compound matters for its role as a versatile building block in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily needed by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), functional materials, and novel agrochemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in kinase inhibitor and other small-molecule therapeutic research.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the quinolinone core's bioactivity.
• Material Science: Serves as a precursor for organic light-emitting diodes (OLEDs) and other functional electronic materials due to its heterocyclic structure.
• Chemical Synthesis: Acts as a versatile building block for further functionalization via cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) or nucleophilic substitutions.
• Academic & Industrial R&D: Employed in research laboratories for method development and exploring new chemical spaces in medicinal and synthetic chemistry.

Basic Information

Product Name	7-Bromo-1-Methylquinolin-2(1H)-One
CAS No.	1187933-12-5
Molecular Formula	C₁₀H₈BrNO
Molecular Weight	238.08 g/mol
Synonyms	7-Bromo-1-methyl-2-quinolinone; 7-Bromo-1-methylquinolin-2(1H)-one; 7-Bromo-1-methyl-1,2-dihydroquinolin-2-one; 1-Methyl-7-bromoquinolin-2(1H)-one; 7-Bromo-1-methyl-2(1H)-quinolinone; 2(1H)-Quinolinone, 7-bromo-1-methyl-
EINECS	Contact for details

Quality Control

Our 7-Bromo-1-Methylquinolin-2(1H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports compliance with cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.