Description

tert-Butyl 7-Bromo-3,4-dihydroquinoline-1(2H)-carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a brominated dihydroquinoline core protected by a Boc (tert-butoxycarbonyl) group. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of complex molecules with potential biological activity. It is primarily needed by R&D scientists and process chemists in the pharmaceutical and biotechnology industries for the development of new drug candidates, particularly in areas requiring sophisticated heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs) and investigational new drugs.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization campaigns to explore new chemical entities.
• Organic Synthesis Building Block: The bromine atom allows for further functionalization via cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig), while the Boc group offers orthogonal protection for the nitrogen.
• Agrochemical Research: Potential use in the development of new crop protection agents and herbicides that utilize quinoline-based chemistries.
• Material Science Precursor: Can be utilized in the research and development of organic electronic materials and functional dyes.

Basic Information

Product Name	tert-Butyl 7-Bromo-3,4-dihydroquinoline-1(2H)-carboxylate
CAS No.	1187932-64-4
Molecular Formula	C14H16BrNO2
Molecular Weight	310.19 g/mol
Synonyms	1-Boc-7-bromo-1,2,3,4-tetrahydroquinoline; 7-Bromo-1,2,3,4-tetrahydroquinoline-1-carboxylic acid tert-butyl ester; tert-Butyl 7-bromo-1,2,3,4-tetrahydroquinoline-1-carboxylate; 7-Bromo-1-Boc-1,2,3,4-tetrahydroquinoline; 1,2,3,4-Tetrahydro-7-bromoquinoline-1-carboxylic acid tert-butyl ester; 7-Bromo-1-(tert-butoxycarbonyl)-1,2,3,4-tetrahydroquinoline; Boc-7-Bromo-THQ
EINECS	Contact for details

Quality Control

Our tert-Butyl 7-Bromo-3,4-dihydroquinoline-1(2H)-carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are available for each lot to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.