Description

1,2,3,4-Tetrahydroquinoline-3-Carboxylic Acid Hydrochloride is a high-purity, pharmaceutically relevant organic building block and salt form. This compound is a critical intermediate in the synthesis of complex molecules, offering a versatile scaffold for medicinal chemistry and drug discovery research. It is primarily utilized by R&D laboratories, CROs, and API manufacturers in the pharmaceutical and agrochemical industries.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new chemical entities.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a precursor in the multi-step synthesis of complex, biologically active molecules.
• Agrochemical Development: Employed in the research and development of new pesticides and herbicides, leveraging the quinoline scaffold.
• Chemical Biology Probes: Utilized in the creation of specialized probes for studying enzyme function and biological pathways.
• Academic & Institutional Research: Supports synthetic organic chemistry projects and methodological development in university and institutional labs.

Basic Information

Product Name	1,2,3,4-Tetrahydroquinoline-3-Carboxylic Acid Hydrochloride
CAS No.	1187931-92-5
Molecular Formula	C10H12NO2·HCl
Molecular Weight	213.67 g/mol
Synonyms	1,2,3,4-Tetrahydroquinoline-3-carboxylic acid hydrochloride; 1,2,3,4-Tetrahydro-3-quinolinecarboxylic acid hydrochloride; 3-Quinolinecarboxylic acid, 1,2,3,4-tetrahydro-, hydrochloride; THQ-3-COOH·HCl; Tetrahydroquinoline-3-carboxylic acid HCl salt; 1,2,3,4-Tetrahydroquinoline-3-carboxylate hydrochloride
EINECS	Contact for details

Quality Control

Our 1,2,3,4-Tetrahydroquinoline-3-Carboxylic Acid Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert conditions or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 97.0% (Total area normalization)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.