Description

(S)-1-(2-Bromo-Phenyl)-Ethylamine Hydrochloride CAS NO 1187931-26-5 is a high-purity chiral amine building block essential for advanced pharmaceutical synthesis and fine chemical research. Its value lies in its role as a key intermediate for constructing complex molecules with defined stereochemistry, enabling the development of novel active pharmaceutical ingredients (APIs). This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications requiring enantiomerically pure intermediates.

Application

• Pharmaceutical Intermediate: A critical chiral building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Asymmetric Synthesis: Used as a chiral auxiliary or resolving agent in stereoselective chemical transformations to produce enantiomerically pure compounds.
• Agrochemical Research: Serves as a precursor in the development of new pesticides and herbicides where specific stereochemistry impacts biological activity.
• Ligand & Catalyst Development: Employed in the preparation of chiral ligands for metal-catalyzed asymmetric reactions.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) exploring new synthetic methodologies.
• Process Chemistry: Used in scale-up and optimization studies for the commercial manufacturing of chiral fine chemicals.

Basic Information

Product Name	(S)-1-(2-Bromo-Phenyl)-Ethylamine Hydrochloride
CAS No.	1187931-26-5
Molecular Formula	C8H11BrClN
Molecular Weight	236.54 g/mol
Synonyms	(S)-1-(2-Bromophenyl)ethan-1-amine hydrochloride; (S)-α-Methyl-2-bromobenzylamine hydrochloride; (1S)-1-(2-Bromophenyl)ethylamine hydrochloride; (S)-(-)-1-(2-Bromophenyl)ethylamine HCl; (S)-2-Bromo-α-methylbenzylamine hydrochloride; (S)-1-(o-Bromophenyl)ethylamine hydrochloride; (S)-1-(2-Bromophenyl)ethylammonium chloride
EINECS	Contact for details

Quality Control

Our (S)-1-(2-Bromo-Phenyl)-Ethylamine Hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high enantiomeric purity. Each lot undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) determination, to meet the stringent requirements of pharmaceutical R&D. A Certificate of Analysis (COA) detailing purity, identity, and chiral purity is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.