Description

3-((1R)-1-Aminoethyl)Benzoic Acid is a high-purity chiral building block featuring a benzoic acid core with a stereodefined aminoethyl side chain. This compound is critical for the synthesis of enantiomerically pure pharmaceuticals and advanced organic materials, where its defined stereochemistry ensures predictable biological activity and material properties. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing novel active ingredients and chiral ligands.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and cardiovascular drug candidates.
• Agrochemical Synthesis: Used in the production of enantiomerically pure herbicides, fungicides, and plant growth regulators where specific stereochemistry enhances efficacy and reduces environmental impact.
• Chiral Ligand/ Catalyst Precursor: Serves as a starting material for synthesizing sophisticated chiral ligands and organocatalysts used in asymmetric synthesis.
• Peptidomimetics Research: Incorporated into peptide analogs and peptidomimetic compounds to modulate stability, bioavailability, and receptor binding affinity.
• Material Science: Employed in the development of chiral polymers and advanced organic frameworks with specific optical or electronic properties.

Basic Information

Product Name	3-((1R)-1-Aminoethyl)Benzoic Acid
CAS No.	1187930-71-7
Molecular Formula	C9H11NO2
Molecular Weight	165.19 g/mol
Synonyms	(R)-3-(1-Aminoethyl)benzoic acid; (1R)-1-(3-Carboxyphenyl)ethanamine; Benzoic acid, 3-[(1R)-1-aminoethyl]-; (R)-1-(3-Carboxyphenyl)ethylamine; 3-[(R)-1-Aminoethyl]benzoic acid; (R)-3-(1-Aminoethyl)benzoate (ionic form); 3-(1-Aminoethyl)benzoic acid (R-enantiomer)
EINECS	Contact for details

Quality Control

Our 3-((1R)-1-Aminoethyl)Benzoic Acid is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets stringent specifications for pharmaceutical R&D. A Certificate of Analysis (COA) detailing identity, purity (typically >98%), enantiomeric excess (typically >99% ee), and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.