Description

(R)-3-(1-Amino-Ethyl)-Benzoic Acid Methyl Ester is a high-value chiral intermediate essential for the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs). This compound matters because its defined stereochemistry is critical for developing drugs with high potency and minimal side effects, particularly in the fields of neurology and cardiology. It is primarily needed by pharmaceutical R&D departments and fine chemical manufacturers engaged in the production of advanced therapeutic agents.

Application

• Key chiral building block for the synthesis of pharmaceutical intermediates and active pharmaceutical ingredients (APIs).
• Critical intermediate in the research and development of central nervous system (CNS) drugs and cardiovascular therapeutics.
• Used in asymmetric synthesis to introduce a chiral benzylic amine moiety into complex molecular architectures.
• Employed in process chemistry for the scale-up and optimization of drug candidate manufacturing routes.
• Serves as a starting material or precursor for custom synthesis and contract manufacturing projects.
• Applicable in academic and industrial research for exploring new synthetic methodologies and biological targets.

Basic Information

Product Name	(R)-3-(1-Amino-Ethyl)-Benzoic Acid Methyl Ester
CAS No.	1187930-21-7
Molecular Formula	C10H13NO2
Molecular Weight	179.22 g/mol
Synonyms	Methyl (R)-3-(1-Aminoethyl)benzoate; (R)-Methyl 3-(1-Aminoethyl)benzoate; Benzoic acid, 3-(1-aminoethyl)-, methyl ester, (R)-; (R)-3-(1-Aminoethyl)benzoic acid methyl ester; (R)-α-Methyl-m-toluic acid methyl ester amine; (R)-Methyl 3-(aminomethyl)benzoate (common misnomer); (R)-1-(3-(Methoxycarbonyl)phenyl)ethan-1-amine
EINECS	Contact for details

Quality Control

Our (R)-3-(1-Amino-Ethyl)-Benzoic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure compliance with exacting standards for pharmaceutical intermediates. A comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.