Description

2-[4-(2-Amino-Ethyl)-Phenyl]-Acetamidine Dihydrochloride is a high-purity, specialized organic salt primarily utilized as a critical building block in advanced pharmaceutical synthesis and chemical research. This compound matters for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs), particularly those targeting neurological and cardiovascular pathways. It is essential for research chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries who require reliable, high-quality intermediates for complex multi-step syntheses.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and cardiovascular therapeutics.
• Chemical Research & Development: Serves as a versatile building block for constructing complex molecular architectures in medicinal chemistry and process optimization.
• Bioconjugation & Probe Synthesis: Used in the development of biochemical probes and diagnostic agents due to its reactive amine and amidine functional groups.
• Peptidomimetic Synthesis: Acts as a core scaffold or side-chain component in the design and synthesis of peptide mimics for therapeutic applications.
• Ligand & Catalyst Development: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Academic & Institutional Research: Supplied to universities and research institutes for fundamental studies in organic synthesis and pharmacology.

Basic Information

Product Name	2-[4-(2-Amino-Ethyl)-Phenyl]-Acetamidine Dihydrochloride
CAS No.	1187930-02-4
Molecular Formula	C10H16N3Cl2 • xH2O (Contact for exact hydrate)
Molecular Weight	Contact for details
Synonyms	4-(2-Aminoethyl)benzeneacetamidine dihydrochloride; 2-[4-(2-Aminoethyl)phenyl]acetamidine dihydrochloride; 2-(4-(2-Aminoethyl)phenyl)acetimidamide dihydrochloride; 1187930-02-4; (4-(2-Aminoethyl)phenyl)methanimidamide dihydrochloride; p-(2-Aminoethyl)benzeneacetamidine dihydrochloride; CAS 1187930-02-4
EINECS	Contact for details

Quality Control

Our 2-[4-(2-Amino-Ethyl)-Phenyl]-Acetamidine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals to ensure it meets the stringent requirements for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.