Description

(S)-1-Cbz-Amino-Butyl-3-Amine Hydrochloride is a high-purity chiral amine derivative, specifically the hydrochloride salt of a Cbz-protected diamine. This compound is a critical chiral building block and intermediate in the synthesis of complex pharmaceutical molecules, offering precise stereochemical control. It is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors engaged in developing active pharmaceutical ingredients (APIs), peptide mimetics, and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Peptide Chemistry: Used in the preparation of modified peptides and peptidomimetics, where the Cbz (carboxybenzyl) protecting group and the amine functionality are strategically utilized.
• Asymmetric Synthesis: Serves as a chiral precursor or ligand in catalytic asymmetric reactions to induce enantioselectivity.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new synthetic methodologies and constructing molecular libraries.
• API Manufacturing: An important building block in the multi-step synthesis of complex, stereochemically defined Active Pharmaceutical Ingredients (APIs).

Basic Information

Product Name	(S)-1-Cbz-Amino-Butyl-3-Amine Hydrochloride
CAS No.	1187927-74-7
Molecular Formula	C₁₂H₁₉ClN₂O₂
Molecular Weight	258.74 g/mol
Synonyms	(S)-1-((Benzyloxy)carbonylamino)-3-aminobutane Hydrochloride; (S)-1-Cbz-1,3-Diaminobutane Hydrochloride; (S)-3-Amino-1-((benzyloxy)carbonylamino)butane Hydrochloride; (S)-1,3-Diaminobutane, N1-Cbz-, Hydrochloride; (S)-N-Cbz-1,3-Diaminobutane Hydrochloride; (S)-1-(N-Cbz-amino)-3-aminobutane Hydrochloride; (S)-1-(Carbobenzyloxyamino)-3-aminobutane Hydrochloride
EINECS	Contact for details

Quality Control

Our (S)-1-Cbz-Amino-Butyl-3-Amine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Recommended storage temperature: 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.