Description

(R)-3-(3-Bromophenoxy)-Pyrrolidine Hcl is a high-purity chiral building block and pharmaceutical intermediate. This compound is valued for its role in the synthesis of complex molecules, particularly in medicinal chemistry and asymmetric synthesis. It is primarily needed by research institutions and pharmaceutical companies developing novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) targets.
• Asymmetric Synthesis: Used as a building block to introduce chirality and the (R)-3-(3-bromophenoxy)-pyrrolidine moiety into more complex molecular architectures.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization processes within drug discovery programs.
• Ligand and Catalyst Development: Serves as a precursor for the synthesis of chiral ligands and organocatalysts used in enantioselective transformations.
• Reference Standard: Used as an analytical standard for quality control and method development in pharmaceutical manufacturing.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying biological pathways and protein interactions.

Basic Information

Product Name	(R)-3-(3-Bromophenoxy)-Pyrrolidine Hydrochloride
CAS No.	1187927-52-1
Molecular Formula	C10H13BrClNO
Molecular Weight	278.57 g/mol
Synonyms	(R)-3-(3-Bromophenoxy)pyrrolidine hydrochloride; (R)-3-(3-Bromophenoxy)-1-azabicyclo[3.3.0]octane HCl; (R)-3-(3-Bromophenoxy)pyrrolidine HCl; Pyrrolidine, 3-(3-bromophenoxy)-, hydrochloride, (3R)-; (3R)-3-(3-Bromophenoxy)pyrrolidine hydrochloride; UNII-Contact for details; (R)-3-(3-Bromo-phenoxy)-pyrrolidine hydrochloride
EINECS	Contact for details

Quality Control

Our (R)-3-(3-Bromophenoxy)-Pyrrolidine Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with research and development grade standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccator to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥97.0%
Chiral Purity (HPLC)	≥98.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.