Description

2-(4-Bromo-Benzyl)-Pyrrolidine Hydrochloride is a high-purity organic building block and pharmaceutical intermediate of significant commercial interest. This compound is valued for its role in the synthesis of more complex molecules, particularly in medicinal chemistry research and development. It is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery of new active pharmaceutical ingredients (APIs) and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of novel drug candidates, particularly those targeting neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes in drug discovery pipelines.
• Chemical Synthesis: Serves as a versatile precursor for the preparation of more complex pyrrolidine and piperidine derivatives with potential biological activity.
• Ligand and Catalyst Development: Employed in the development of chiral ligands and organocatalysts for asymmetric synthesis.
• Academic Research: Utilized in university and institutional labs for methodological development and the study of heterocyclic chemistry.
• Reference Standard: Can be supplied as a high-purity standard for analytical method development and quality control in API manufacturing.

Basic Information

Product Name	2-(4-Bromo-Benzyl)-Pyrrolidine Hydrochloride
CAS No.	1187927-02-1
Molecular Formula	C11H14BrN•HCl
Molecular Weight	276.60 g/mol
Synonyms	2-[(4-Bromophenyl)methyl]pyrrolidine hydrochloride; 1-(4-Bromobenzyl)pyrrolidine-2-hydrochloride; 4-Bromo-α-(2-pyrrolidinylmethyl)benzene hydrochloride; Pyrrolidine, 2-[(4-bromophenyl)methyl]-, hydrochloride (1:1); 2-(4-Bromobenzyl)pyrrolidine HCl
EINECS	Contact for details

Quality Control

Our 2-(4-Bromo-Benzyl)-Pyrrolidine Hydrochloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality system is designed to meet the stringent requirements of the pharmaceutical and fine chemical industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.