Description

4-Bromo-2-T-Butoxy-1-Nitrobenzene is a specialized aromatic nitro compound featuring both bromo and tert-butoxy substituents, making it a valuable synthetic intermediate. This compound matters for its role in facilitating complex organic transformations, particularly in the construction of advanced pharmaceutical scaffolds and functional materials. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications in cross-coupling reactions and as a precursor to more complex molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), especially those requiring a substituted nitrobenzene core.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides.
• Material Science Research: Serves as a monomer or precursor in the development of organic electronic materials, dyes, and pigments.
• Cross-Coupling Reactions: Acts as a substrate in Suzuki, Buchwald-Hartwig, and other palladium-catalyzed coupling reactions due to the reactive bromo substituent.
• Academic & Industrial R&D: Employed in chemical libraries for high-throughput screening and discovery chemistry programs.
• Ligand and Catalyst Development: Useful for synthesizing novel ligands for metal complexes used in catalysis.

Basic Information

Product Name	4-Bromo-2-T-Butoxy-1-Nitrobenzene
CAS No.	1187386-34-0
Molecular Formula	C10H12BrNO3
Molecular Weight	274.11 g/mol
Synonyms	1-Bromo-4-tert-butoxy-2-nitrobenzene; 4-Bromo-2-(tert-butoxy)-1-nitrobenzene; 2-tert-Butoxy-4-bromo-1-nitrobenzene; 4-Bromo-2-tert-butoxynitrobenzene; 1-Nitro-4-bromo-2-tert-butoxybenzene; Benzene, 1-bromo-4-(1,1-dimethylethoxy)-2-nitro-; 4-Bromo-2-(1,1-dimethylethoxy)-1-nitrobenzene
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-T-Butoxy-1-Nitrobenzene is produced under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing specifications such as assay (HPLC), identity (IR, NMR), and impurity profile is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Heavy Metals	≤20 ppm
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.