Description

1-Cbz-3-(Aminomethyl)Piperidine Hydrochloride is a high-purity, protected piperidine derivative essential for advanced organic synthesis and pharmaceutical research. This compound serves as a critical versatile building block for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking reliable, high-quality intermediates for their synthetic pipelines.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of novel drug candidates, particularly those targeting the central nervous system (CNS).
• Peptidomimetic Chemistry: Used to introduce constrained piperidine scaffolds into peptide backbones to enhance metabolic stability and bioavailability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and receptor interactions.
• Agrochemical Research: Acts as an intermediate in the development of new crop protection agents and herbicides.
• Custom Synthesis & Scale-Up: A reliable starting material for contract research organizations (CROs) and CDMOs for custom synthesis projects from milligram to kilogram scale.

Basic Information

Item	Detail
Product Name	1-Cbz-3-(Aminomethyl)Piperidine Hydrochloride
CAS No.	1186663-23-9
Molecular Formula	C14H21ClN2O2
Molecular Weight	284.78 g/mol
Synonyms	1-[(Benzyloxy)carbonyl]-3-(aminomethyl)piperidine hydrochloride; 3-(Aminomethyl)-1-Cbz-piperidine hydrochloride; 1-N-Cbz-3-(aminomethyl)piperidine HCl; N-Carbobenzoxy-3-(aminomethyl)piperidine hydrochloride; 3-(Aminomethyl)piperidine-1-carboxylic acid benzyl ester hydrochloride; (Piperidin-3-ylmethyl)carbamic acid benzyl ester hydrochloride; 1-Cbz-3-piperidinemethylamine hydrochloride
EINECS	Contact for details

Quality Control

Our 1-Cbz-3-(Aminomethyl)Piperidine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing including HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP standards for pharmaceutical intermediates, ensuring reliability for your most critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. For long-term storage, consider storing at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.