Description

4'-Chloro-3'-Fluoro[1,1'-Biphenyl]-4-Carbohydrazide is a high-purity, functionalized biphenyl derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both chloro and fluoro substituents alongside a reactive carbohydrazide group, makes it an invaluable intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and crop protection agent discovery.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in scaffolds targeting central nervous system (CNS) and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of next-generation herbicides and fungicides, where the halogenated biphenyl core contributes to biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers or luminescent compounds, due to its conjugated biphenyl system.
• Custom Chemical Synthesis: Provides a versatile starting point for contract research organizations (CROs) and fine chemical manufacturers producing bespoke compounds for client projects.

Basic Information

Product Name	4'-Chloro-3'-Fluoro[1,1'-Biphenyl]-4-Carbohydrazide
CAS No.	1186404-82-9
Molecular Formula	C13H10ClFN2O
Molecular Weight	264.68 g/mol
Synonyms	4'-Chloro-3'-fluorobiphenyl-4-carbohydrazide; (4'-Chloro-3'-fluoro[1,1'-biphenyl]-4-yl)carbohydrazide; 4-Carbohydrazide-4'-chloro-3'-fluorobiphenyl; 4-Hydrazinylcarbonyl-4'-chloro-3'-fluorobiphenyl; Biphenyl-4-carbohydrazide, 4'-chloro-3'-fluoro-; 1186404-82-9; 4'-Chloro-3'-fluoro-1,1'-biphenyl-4-carbohydrazide
EINECS	Contact for details

Quality Control

Our 4'-Chloro-3'-Fluoro[1,1'-Biphenyl]-4-Carbohydrazide is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the exacting standards required for research and scale-up applications. A detailed Certificate of Analysis (COA) is provided with each shipment, and we support custom purity requirements to fit specific project needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.