Description

(E)-3-(2-Chloro-6-Methylquinolin-3-Yl)-1-(4-Methoxyphenyl)Prop-2-En-1-One CAS NO 1186396-66-6 is a high-purity, synthetic organic compound belonging to the chalcone-quinoline hybrid class. This molecule is of significant commercial interest as a key pharmaceutical intermediate and a versatile building block for advanced material science research. It is primarily sought by R&D and manufacturing teams in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly those targeting anti-inflammatory, anticancer, or antimicrobial pathways.
• Agrochemical Research: Used as a building block for developing new-generation pesticides and herbicides due to its bioactive quinoline core.
• Material Science: Investigated for the development of organic semiconductors, non-linear optical (NLO) materials, and advanced polymers.
• Chemical Synthesis: Acts as a versatile scaffold in organic chemistry for constructing complex heterocyclic compounds via further cyclization or functionalization reactions.
• Biochemical Probe: Utilized in academic and industrial research as a tool compound to study biological mechanisms and protein interactions.

Basic Information

Product Name	(E)-3-(2-Chloro-6-Methylquinolin-3-Yl)-1-(4-Methoxyphenyl)Prop-2-En-1-One
CAS No.	1186396-66-6
Molecular Formula	C20H16ClNO2
Molecular Weight	337.80 g/mol
Synonyms	(E)-1-(4-Methoxyphenyl)-3-(2-chloro-6-methylquinolin-3-yl)prop-2-en-1-one; 3-(2-Chloro-6-methyl-3-quinolinyl)-1-(4-methoxyphenyl)-2-propen-1-one; 2-Chloro-6-methyl-3-[3-(4-methoxyphenyl)-3-oxo-1-propen-1-yl]quinoline; Chalcone-quinoline hybrid; Quinolinyl chalcone derivative; 1186396-66-6; AKOS025311193
EINECS	Contact for details

Quality Control

Every batch of our (E)-3-(2-Chloro-6-Methylquinolin-3-Yl)-1-(4-Methoxyphenyl)Prop-2-En-1-One is manufactured under a strict quality management system. We guarantee high purity and batch-to-batch consistency through rigorous analytical protocols including HPLC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to ensure compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.