Description

tert-Butyl 3-(4-Bromophenyl)-1,2,3,4-tetrahydroquinoxaline-1-carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a complex heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology research. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex drug candidates, especially those targeting neurological disorders.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR) around the quinoxaline scaffold.
• CNS Drug Development: Serves as a core structure for developing potential treatments for conditions such as depression, anxiety, and neurodegenerative diseases.
• Oncological Agent Synthesis: Employed in the construction of molecules designed to inhibit specific kinases or other cancer-related targets.
• Chemical Biology Probes: Utilized to create tool compounds for studying biological pathways and protein functions in academic and industrial research settings.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds under cGMP or non-GMP conditions.

Basic Information

Product Name	tert-Butyl 3-(4-Bromophenyl)-1,2,3,4-tetrahydroquinoxaline-1-carboxylate
CAS No.	1186194-93-3
Molecular Formula	C19H19BrN2O2
Molecular Weight	387.27 g/mol
Synonyms	1,2,3,4-Tetrahydroquinoxaline-1-carboxylic acid, 3-(4-bromophenyl)-, 1,1-dimethylethyl ester; 1-(tert-Butoxycarbonyl)-3-(4-bromophenyl)-1,2,3,4-tetrahydroquinoxaline; 3-(4-Bromophenyl)-1,2,3,4-tetrahydroquinoxaline-1-carboxylic acid tert-butyl ester; tert-Butyl 3-(p-bromophenyl)-1,2,3,4-tetrahydro-1-quinoxalinecarboxylate; Boc-3-(4-Bromophenyl)-1,2,3,4-tetrahydroquinoxaline; 1186194-93-3
EINECS	Contact for details

Quality Control

Our production of tert-Butyl 3-(4-Bromophenyl)-1,2,3,4-tetrahydroquinoxaline-1-carboxylate adheres to stringent quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure compliance with research and development specifications. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, open flames, and incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Individual impurity ≤ 1.0%
Total Impurities	≤ 3.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.