Description

2-Piperazin-1-Yl-Isonicotinonitrile Hydrochloride, 98+% C10H13Cln4, Mw: 224.69 is a high-purity, heterocyclic organic compound primarily utilized as a critical building block in advanced chemical synthesis. Its value lies in its role as a versatile intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. This product is essential for medicinal chemists and process development scientists working in drug discovery, agrochemical research, and the synthesis of specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Medicinal Chemistry Research: Used extensively in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR) due to its piperazine and cyanopyridine motifs.
• Agrochemical Synthesis: Serves as a building block for developing new active ingredients in crop protection products, such as herbicides and fungicides.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and target validation.
• Library Synthesis for High-Throughput Screening: A valuable scaffold for generating diverse compound libraries to identify new bioactive molecules.
• Fine Chemical Production: Used in the multi-step synthesis of complex, high-value specialty chemicals beyond the life sciences sector.

Basic Information

Product Name	2-Piperazin-1-Yl-Isonicotinonitrile Hydrochloride
CAS No.	1185316-24-8
Molecular Formula	C10H13ClN4
Molecular Weight	224.69 g/mol
Synonyms	2-(Piperazin-1-yl)isonicotinonitrile hydrochloride; 2-(1-Piperazinyl)-4-pyridinecarbonitrile hydrochloride; 4-Cyano-2-(piperazin-1-yl)pyridine hydrochloride; 2-Piperazin-1-ylpyridine-4-carbonitrile hydrochloride; Isonicotinonitrile, 2-(1-piperazinyl)-, hydrochloride; 2-(Piperazin-1-yl)pyridine-4-carbonitrile HCl; 2-Piperazin-1-yl-isonicotinonitrile HCl
EINECS	Contact for details

Quality Control

Our 2-Piperazin-1-Yl-Isonicotinonitrile Hydrochloride is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing to ensure it meets the specified 98+% purity and consistent quality for research and development applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.