Description

1-Methyl-2-(Piperidin-3-Yloxy)-1H-Benzoimidazole Hydrochloride, 98+% C13H18Cln3O, Mw: 267.76 CAS NO 1185313-72-7 is a high-purity, complex heterocyclic compound featuring a benzimidazole core linked to a piperidine moiety via an ether bridge, presented as its hydrochloride salt. This compound is of significant interest as a key synthetic intermediate or potential pharmacologically active scaffold in advanced organic synthesis. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new therapeutic agents, particularly in areas like kinase inhibition or central nervous system (CNS) targeting.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel drug candidates, especially those targeting protein kinases or neurological receptors.
• Biochemical Research: Used as a reference standard or a probe molecule in biological assays to study enzyme inhibition and cellular signaling pathways.
• Medicinal Chemistry: Acts as a core scaffold for structure-activity relationship (SAR) studies to optimize potency, selectivity, and pharmacokinetic properties of lead compounds.
• Fine Chemical Synthesis: Employed in multi-step synthetic routes to create more complex, functionalized heterocyclic systems for specialized applications.
• Contract Research & Development (CRO/CMO): Supplied to organizations providing custom synthesis and process development services for the life sciences industry.
• Academic Research: Utilized in university and institutional labs for exploratory research in organic chemistry and drug discovery projects.

Basic Information

Product Name	1-Methyl-2-(Piperidin-3-Yloxy)-1H-Benzoimidazole Hydrochloride
CAS No.	1185313-72-7
Molecular Formula	C13H18ClN3O
Molecular Weight	267.76 g/mol
Synonyms	1-Methyl-2-(3-piperidinyloxy)-1H-benzimidazole hydrochloride; 1H-Benzimidazole, 1-methyl-2-(3-piperidinyloxy)-, hydrochloride; 2-(Piperidin-3-yloxy)-1-methyl-1H-benzoimidazole hydrochloride; 1-Methyl-2-(piperidin-3-yloxy)-1H-benzoimidazole HCl; 1185313-72-7; 1-Methyl-2-(3-piperidyloxy)benzimidazole hydrochloride
EINECS	Contact for details

Quality Control

Our 98+% purity grade of 1-Methyl-2-(Piperidin-3-Yloxy)-1H-Benzoimidazole Hydrochloride is produced under strict quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the exacting standards required for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.