Description

[1-(6-Chloro-Pyridin-3-Ylmethyl)-Piperidin-3-Yl]-Methanol Dihydrochloride is a high-purity (98+%) organic salt with the molecular formula C12H19Cl3N2O and a molecular weight of 313.65. This compound is a critical advanced pharmaceutical intermediate valued for its defined chemical structure and high purity, which are essential for ensuring batch-to-batch consistency in complex synthesis. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development and production of active pharmaceutical ingredients (APIs).

Application

This high-purity intermediate is designed for specialized chemical synthesis, particularly in the life sciences sector. Its primary and related applications include:

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of novel drug candidates, especially in central nervous system (CNS) and other therapeutic areas.
• Chemical Research & Development: Used in academic and industrial R&D labs for method development, structure-activity relationship (SAR) studies, and process chemistry optimization.
• Reference Standard: Serves as a high-purity analytical standard for quality control, method validation, and regulatory submissions.
• Agrochemical Synthesis: Potential use as an intermediate in the development of advanced crop protection agents.
• Ligand and Catalyst Development: Utilized in the preparation of complex ligands for catalytic systems or metal-organic frameworks (MOFs).

Basic Information

Product Name	[1-(6-Chloro-Pyridin-3-Ylmethyl)-Piperidin-3-Yl]-Methanol Dihydrochloride
CAS No.	1185312-32-6
Molecular Formula	C12H19Cl3N2O
Molecular Weight	313.65 g/mol
Synonyms	(1-[(6-Chloropyridin-3-yl)methyl]piperidin-3-yl)methanol dihydrochloride; 1-[(6-Chloro-3-pyridinyl)methyl]-3-piperidinemethanol dihydrochloride; 3-Piperidinemethanol, 1-[(6-chloro-3-pyridinyl)methyl]-, dihydrochloride; (1-((6-Chloropyridin-3-yl)methyl)piperidin-3-yl)methanol dihydrochloride; 6-Chloro-3-((3-(hydroxymethyl)piperidin-1-yl)methyl)pyridine dihydrochloride; CAS 1185312-32-6; [1-(6-Chloro-3-pyridylmethyl)piperidin-3-yl]methanol dihydrochloride
EINECS	Contact for details

Quality Control

Our [1-(6-Chloro-Pyridin-3-Ylmethyl)-Piperidin-3-Yl]-Methanol Dihydrochloride is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing to confirm identity, purity, and consistency, meeting the specifications required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) providing batch-specific results for assay, impurities, and other critical parameters is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed to minimize exposure to atmospheric moisture and light to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.