Description

4-Amino-3,4,5,6-tetrahydro-2H-[1,2']bipyridinyl-4'-carbonitrile hydrochloride is a high-purity, advanced pharmaceutical intermediate with a molecular weight of 238.72. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of complex molecules for therapeutic development. It is primarily needed by research institutions and pharmaceutical companies engaged in the discovery and production of novel active pharmaceutical ingredients (APIs).

Application

This specialized bipyridine derivative serves as a versatile synthon in organic synthesis, with key applications including:

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of complex drug candidates, particularly in central nervous system (CNS) and cardiovascular research.
• Ligand Synthesis: Used to construct sophisticated nitrogen-containing ligands for catalysis and metal-organic frameworks (MOFs).
• Agrochemical Research: Serves as a building block for developing novel crop protection agents and herbicides.
• Chemical Biology Probes: Employed in the design of molecular probes for studying enzyme function and biological pathways.
• Material Science: A potential monomer or additive in the development of specialty polymers and functional materials.

Basic Information

Product Name	4-Amino-3,4,5,6-tetrahydro-2H-[1,2']bipyridinyl-4'-carbonitrile hydrochloride
CAS No.	1185309-64-1
Molecular Formula	C11H15ClN4
Molecular Weight	238.72 g/mol
Synonyms	4-Amino-3,4,5,6-tetrahydro-2H-[1,2'-bipyridine]-4'-carbonitrile hydrochloride; 4'-Cyano-3,4,5,6-tetrahydro-2H-[1,2']bipyridinyl-4-ylamine hydrochloride; 4-Amino-4'-cyano-3,4,5,6-tetrahydro-2H-[1,2']bipyridinyl hydrochloride; 1,2,3,6-Tetrahydropyridin-4-yl-[1,2']bipyridinyl-4'-carbonitrile hydrochloride; 4-Amino-4'-cyano-1,2,3,6-tetrahydro-2,2'-bipyridine hydrochloride; 4-Amino-4'-cyano-1,2,3,6-tetrahydro-[2,2']bipyridinyl hydrochloride
EINECS	Contact for details

Quality Control

Our 4-Amino-3,4,5,6-tetrahydro-2H-[1,2']bipyridinyl-4'-carbonitrile hydrochloride is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure a purity of 98+% and compliance with research-grade specifications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency for your critical R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic nature, store under dry, inert conditions (e.g., nitrogen atmosphere) at a controlled room temperature (15-25°C). Keep the container in a cool, dry, and well-ventilated area, separate from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.