Description

3-(4-Amino-Piperidin-1-Yl)-1-Phenylpropan-1-One Hydrochloride is a high-purity, non-racemic chiral building block and intermediate of significant interest in advanced organic synthesis. This compound matters because it provides a critical, functionalized piperidine scaffold essential for constructing complex molecules with high stereochemical fidelity. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the discovery and process development of new active ingredients, particularly those targeting neurological and metabolic pathways.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of novel drug candidates, especially for central nervous system (CNS) and metabolic disease targets.
• Agrochemical Research: Used in the development of new pesticides and herbicides where the piperidine moiety confers specific biological activity.
• Chemical Biology & Proteomics: Serves as a versatile scaffold for creating molecular probes and activity-based protein profiling (ABPP) reagents.
• Asymmetric Catalysis Ligand Synthesis: Employed in the preparation of chiral ligands and organocatalysts for enantioselective transformations.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for clients.
• Academic Research: Utilized in university and institutional labs for methodological development in synthetic organic chemistry and medicinal chemistry programs.

Basic Information

Product Name	3-(4-Amino-Piperidin-1-Yl)-1-Phenylpropan-1-One Hydrochloride
CAS No.	1185308-38-6
Molecular Formula	C14H21ClN2O
Molecular Weight	268.79 g/mol
Synonyms	1-Propanone, 3-(4-amino-1-piperidinyl)-1-phenyl-, hydrochloride; 3-(4-Aminopiperidin-1-yl)-1-phenylpropan-1-one HCl; 3-(4-Amino-1-piperidinyl)-1-phenyl-1-propanone hydrochloride; 1-Phenyl-3-(4-aminopiperidin-1-yl)propan-1-one hydrochloride; 4-Amino-1-[3-oxo-3-phenylpropyl]piperidine hydrochloride; (RS)-3-(4-Aminopiperidin-1-yl)-1-phenylpropan-1-one hydrochloride; 1185308-38-6; AKOS025147064
EINECS	Contact for details

Quality Control

Our 3-(4-Amino-Piperidin-1-Yl)-1-Phenylpropan-1-One Hydrochloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the specified 98+% purity grade. Certificates of Analysis (COA) with detailed chromatographic data are provided and available upon request to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.