Description

4-Methoxy-2-(Trifluoromethyl)Aniline Hydrochloride is a high-purity, advanced pharmaceutical intermediate characterized by its aniline core substituted with methoxy and trifluoromethyl groups. This compound is critical for the synthesis of complex molecules, offering a versatile building block for introducing specific aromatic and fluorine-containing motifs. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, leveraging the stability imparted by the trifluoromethyl group.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands in catalytic processes and material science.
• Dye and Pigment Research: Acts as an intermediate in the development of specialized dyes and functional colorants.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex aromatic structures in fine chemical production.

Basic Information

Product Name	4-Methoxy-2-(Trifluoromethyl)Aniline Hydrochloride
CAS No.	1185304-48-6
Molecular Formula	C9H9ClF3NO
Molecular Weight	239.62 g/mol
Synonyms	2-Amino-5-methoxybenzotrifluoride hydrochloride; 4-Methoxy-2-(trifluoromethyl)benzenamine hydrochloride; 2-Trifluoromethyl-4-methoxyaniline hydrochloride; 5-Methoxy-2-(trifluoromethyl)aniline hydrochloride; 4-Methoxy-α,α,α-trifluoro-o-toluidine hydrochloride; Aniline, 4-methoxy-2-(trifluoromethyl)-, hydrochloride; 2-(Trifluoromethyl)-4-methoxyaniline hydrochloride
EINECS	Contact for details

Quality Control

Our 4-Methoxy-2-(Trifluoromethyl)Aniline Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing all specifications are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed and away from moisture and direct light exposure.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.