Description

1,3,5-Trimethyl-1H-Pyrazol-4-Amine Hydrochloride is a high-purity, functionalized pyrazole derivative offered as a stable hydrochloride salt. This compound serves as a critical pharmaceutical intermediate and versatile organic building block for advanced chemical synthesis. It is primarily utilized by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries to construct complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing functionalized pyrazole cores.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands in coordination chemistry and catalysis.
• Organic Building Block: Employed in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Material Science Research: Investigated as a monomer or functional additive in the development of advanced polymers and functional materials.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for biochemical and cellular studies.

Basic Information

Product Name	1,3,5-Trimethyl-1H-Pyrazol-4-Amine Hydrochloride
CAS No.	1185303-62-1
Molecular Formula	C6H12N3·HCl
Molecular Weight	161.64 g/mol (Free base) / 198.09 g/mol (Hydrochloride)
Synonyms	4-Amino-1,3,5-trimethyl-1H-pyrazole hydrochloride; 1,3,5-Trimethyl-4-aminopyrazole hydrochloride; 1H-Pyrazol-4-amine, 1,3,5-trimethyl-, hydrochloride (1:1); 1,3,5-Trimethylpyrazol-4-ylamine hydrochloride; 4-Amino-1,3,5-trimethylpyrazole HCl; TMPA·HCl
EINECS	Contact for details

Quality Control

Our 1,3,5-Trimethyl-1H-Pyrazol-4-Amine Hydrochloride is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical quality attributes are provided with each shipment to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent moisture absorption. Recommended long-term storage at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.